Moving liquids around is at the core of many automation workflows. What are our options for doing this on the Jubilee?…

OT-2 pipette tool

building/use documentation

Pros:

  • Semi-commercial product with some known characteristics
  • Build and use instructions for Jubilee exist

Cons:

  • Expensive ($2500!)

Syringe tool

build/use documentation

Pros:

  • We were gifted one…so nothing to build (but even if you had to build, this is relatively low cost)

Cons:

  • No ejectable tips; if worried about contamination, need to wash the end of the syringe

Digital Pipette (from Alan & co.)

build/use documentation

Pros:

  • Very simple construction/assembly

Cons:

  • Really just a syringe
  • Notionally, 10 mL volume (not a micropipette)
  • No tip ejection/replacement

Open Lab Automation Pipette

build/use documentation

Pros:

  • All open-source solution, relatively low cost
  • Tip ejection (by pulling against a fork structure)
  • Claims 2-1000 uL range, when used with appropriate tips

Cons:

  • Looks a bit top-heavy, and construction has some complications

Clip tip

build/use documentation

Pros:

  • Relatively simple construction: Main mechanism is a Thermo ClipTip replacement assembly ($150) and a linear stepper ($100) with minimal 3d-printed parts and limit switch to attach
  • Tip ejection achieved by pulling against a fork structure
  • Clip tip assemblies are availabile in different ranges

Cons:

  • Needs mechanical & configuration adaptation for Jubilee
  • Needs appropriate calibration